Dilue

Dilution calculator fortirzepatide and retatrutide

Precise calculations, impeccable experience. Built for those who take care seriously.

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How the dilution calculation works

Tirzepatide and retatrutide are GLP-1 analogs that, in a vial, come as a powder and need to be reconstituted. Reconstituting means dissolving the powder in bacteriostatic water and then drawing into the syringe the volume that matches your dose. It is three simple calculations, and the calculator does all of them for you.

  1. 1

    Concentration

    Vial strength divided by the bacteriostatic water. The result is in mg per ml.

  2. 2

    Dose volume

    Desired dose divided by the concentration. The result is the volume in ml.

  3. 3

    Units in the syringe

    Dose volume divided by the syringe total volume, multiplied by the total units. A 1 ml syringe has 100 IU.

Example

A 10 mg vial reconstituted with 1 ml of water becomes 10 mg/ml. For a 2.5 mg dose you draw 0.25 ml, which is 25 IU on a 1 ml syringe.

mg to IU conversion table

How many units to draw for each dose, already using the recommended bacteriostatic water and a 1 ml (100 IU) syringe. For other syringes or water volumes, use the calculator above.

Tirzepatide

mg to IU conversion for Tirzepatide on a 1 ml syringe
Vial2.5 mg5 mg7.5 mg10 mg12.5 mg15 mg
2.5 mg0.5 ml water · 5 mg/ml50 IU-----
5 mg0.5 ml water · 10 mg/ml25 IU50 IU----
7.5 mg0.5 ml water · 15 mg/ml17 IU33 IU50 IU---
10 mg1 ml water · 10 mg/ml25 IU50 IU75 IU100 IU--
12.5 mg1 ml water · 12.5 mg/ml20 IU40 IU60 IU80 IU100 IU-
15 mg1 ml water · 15 mg/ml17 IU33 IU50 IU67 IU83 IU100 IU
20 mg1 ml water · 20 mg/ml13 IU25 IU38 IU50 IU63 IU75 IU
30 mg1.5 ml water · 20 mg/ml13 IU25 IU38 IU50 IU63 IU75 IU

Retatrutide

Retatrutide is an investigational compound, with no ANVISA or FDA approval. The values below are only the dilution math.

mg to IU conversion for Retatrutide on a 1 ml syringe
Vial2 mg4 mg6 mg8 mg12 mg
5 mg0.5 ml water · 10 mg/ml20 IU40 IU---
8 mg0.5 ml water · 16 mg/ml13 IU25 IU38 IU50 IU-
10 mg1 ml water · 10 mg/ml20 IU40 IU60 IU80 IU-
12 mg1 ml water · 12 mg/ml17 IU33 IU50 IU67 IU100 IU
15 mg1 ml water · 15 mg/ml13 IU27 IU40 IU53 IU80 IU
20 mg1 ml water · 20 mg/ml10 IU20 IU30 IU40 IU60 IU
24 mg1 ml water · 24 mg/ml8 IU17 IU25 IU33 IU50 IU

Values are rounded to the nearest syringe mark. To check the effective dose of each combination, use the calculator above.

Frequently asked questions

What is Dilue for?
Dilue is a free calculator that works out the dilution (reconstitution) of GLP-1 analogs such as tirzepatide and retatrutide. You enter the vial strength, the amount of bacteriostatic water and the desired dose, and it shows how many ml to draw and how many units to mark on the insulin syringe.
What is bacteriostatic water?
It is sterile water with 0.9% benzyl alcohol, a preservative that stops bacteria from growing. That is why it is used to reconstitute peptides that will be stored and used across several doses over weeks.
How do I convert mg to IU?
IU is a volume mark on the insulin syringe, not a unit of mass. You first work out the concentration (mg per ml) and the dose volume in ml, then convert that volume to IU. The calculator does the three steps at once.
How many units should I draw?
It depends on the vial strength, the amount of water used, the desired dose and the syringe. Choose the compound above, enter those values and the calculator shows exactly how many units to mark.
How long does the reconstituted vial last in the fridge?
Once reconstituted, the peptide is usually kept refrigerated between 2 and 8 degrees. The real shelf life depends on the product and the manufacturer instructions, so always check the label or lab report and talk to your doctor.
Which syringe should I use?
Insulin syringes of 0.3 ml (30 IU), 0.5 ml (50 IU) and 1 ml (100 IU) all work. Smaller volumes give more precision for small doses, the 1 ml one fits larger volumes. The calculator adjusts the result to the chosen syringe.
Why is the dose not always a round number of units?
The syringe only has marks every 1 IU (or every 0.5 IU on the 30 IU ones). When the math lands between two marks, the calculator rounds to the nearest one and shows the effective dose. Adjusting the water usually makes the number round.
Does it work for compounded tirzepatide and for the pen?
The dilution math is the same for any powder vial, whether compounded or from other brands. The calculator only depends on the strength in mg and the water used. Prefilled pens come already diluted and need no reconstitution.
Is retatrutide approved?
No. Retatrutide is a compound in clinical trials, with no ANVISA or FDA approval. The content here is only informational about the dilution math and is not an encouragement to use it.
Does Dilue replace medical advice?
No. Dilue is an educational calculation tool. Decisions about treatment, dose and follow-up are your doctor's. Use the calculator to check the preparation, not to define care.
Do I have to pay or create an account?
No. The calculator is free and asks for no signup. Just choose the compound, enter the values and see the result.